During my PhD studies I was mainly involved in the analysis of the dynamical properties of cardiovascular signals, especially microcirculatory blood flow time series, as measured by the laser-Doppler flowmetry (LDF) method. By applying spectral analysis in the time-frequency domain, using the wavelet transform and the Morlet mother wavelet, low frequency oscillations are revealed from the LDF signals. Investigation of these oscillations in different diseases or during vasoactive stimulation provides information about the processes involved in regulation of the blood flow.
My recent research interest is focused on transit times of cardiac-related pulses, detected by LDF in the capillary bed. These transit times are related to the state of the microcirculation and show a promising approach for accessing the functioning of the endothelium.